Wednesday, 15 July, 2020
The DIYer's Combo Deal - Save $9.90
WP_Post Object ( [ID] => 3388 [post_author] => 638 [post_date] => 2018-04-01 17:09:40 [post_date_gmt] => 2018-04-01 07:09:40 [post_content] => Three essential tools for every handyman or woman. Includes our magnetic WristBuddy, an extendable, flexible magnetic flashlight and our three function COB headlamp!

1 - Magnetic WristBuddy:

The magnetic WristBuddy keeps everything within easy reach whether you’re under the hood, squeezing into a bathroom cabinet, up a ladder or just nailing a few 4×2’s together! Designed to hold lots of screws, nails, nuts and washers, the magnets are amply strong enough to also hold drill bits, hex keys, bolts, screwdrivers and even spanners. Made from extremely durable 1680D Oxford cloth, your WristBuddy will be with you for years to come.

2 - Magnetic, Extendable, Flexible Flashlight

  The perfect tool for finding that lost screw that rolled under your workbench or the pins that dropped onto the carpet! This bright, COB LED flashlight extends to a full 60cm (2ft), has a flexible neck and a strong magnet in the lens surround. It's also a wonderful aid for anyone with bad knees.

3 - Three Function COB LED Headlamp

How often have you wished for better lighting while doing a job? All you needed was a third hand with a flashlight, right? This tough, fully adjustable headlamp uses the latest Chip On Board LED technology for maximum performance. Set it for bright, normal or strobe function with a click of the switch. Weighing just 65 grams (2.25 oz), including the three AAA batteries, our headlamp can be worn hour after hour. And because it's both shock and water resistant, it's great for camping and fishing as well as in the home and workshop.

Special offer:

Bought separately, these three items are currently selling for a combined total of $27.40. For this week only, we have packaged all three for just $17.50 including free delivery. Please note that there is a limit of three combo packs per customer. [add_to_cart id="3388"]   [post_title] => The DIYer's Combo Deal [post_excerpt] => Three essential tools for every handyman or woman. Includes our magnetic WristBuddy, an extendable, flexible magnetic flashlight and our high-powered COB headlamp! The perfect gift for any DIYer! Maximum of three combo packs per customer. [post_status] => publish [comment_status] => open [ping_status] => closed [post_password] => [post_name] => the-diyers-combo-deal [to_ping] => [pinged] => [post_modified] => 2019-03-11 00:01:10 [post_modified_gmt] => 2019-03-11 00:01:10 [post_content_filtered] => [post_parent] => 0 [guid] => http://deals.thediy.market/?post_type=product&p=3388 [menu_order] => 0 [post_type] => product [post_mime_type] => [comment_count] => 11 [filter] => raw )
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Diabetic Mice Cured Using Human Stem Cells

Diabetic Mice Cured Using Human Stem Cells

No field of biotechnology seems to have promised more but delivered so little in the way of treatments than embryonic stem cells. The cells – which scientists cull from IVF embryos – are capable of developing into any other tissue type in the body.

The process holds the promise of an unlimited supply of healthy replacement tissue for people suffering from various diseases.

While the procedure might sound straightforward, realizing its potential hasn’t been that at all.

Scientists have only been able to carry out a handful of human studies. None have yielded significant results.

Recently, however, researchers from the Washington University School of Medicine in St. Louis made what many say could be an important breakthrough.

The scientists successfully used human stem cells to cure diabetes in mice. They achieved this by creating insulin-producing cells from human stem cells and injecting them into mice.

Researchers successfully converted human stem cells into cells capable of producing insulin.
Researchers from the Washington University School of Medicine in St. Louis successfully converted human stem cells into cells capable of producing insulin.

Curing Diabetic Mice

“These mice had very severe diabetes with blood sugar readings of more than 500 milligrams per deciliter of blood – levels that could be fatal for a person – and when we gave the mice the insulin-secreting cells, within two weeks their blood glucose levels had returned to normal and stayed that way for many months,” lead researcher Jeffrey Millman said in a statement.

Because their bodies attack the pancreatic cells that control blood glucose, type 1 diabetics must regularly measure their blood sugar levels with finger pricks. Many also need to inject insulin multiple times a day.

Yet even with constant injections, the lives of people who suffer from type 1 diabetes can be foreshortened by more than a decade.

This is where the research team’s work may one day save lives.

Because their bodies attack the pancreatic cells that control blood glucose, type 1 diabetics must regularly measure their blood sugar levels with finger pricks.
Because their bodies attack the pancreatic cells that control blood glucose, type 1 diabetics must regularly measure their blood sugar levels with finger pricks.

A Better Approach

The team’s research – outlined in a paper published recently in Nature Biotechnology – builds on previous studies.

Scientists had earlier figured out how to create insulin-producing cells out of human stem cells. But they have been unable to demonstrate the effectiveness in mice – until now.

The difficulty lay in the off-target cells created during the attempt to produce new beta cells, Millman explains.  

“You need about a billion beta cells to cure a person of diabetes,” he says. “But if a quarter of the cells you make are actually liver cells or other pancreas cells, instead of needing a billion cells, you’ll need 1.25 billion cells.”

Scientists had earlier figured out how to create insulin-producing cells out of human stem cells.
Scientists had earlier figured out how to create insulin-producing cells out of human stem cells.

The new method concentrates on the cells’ internal scaffolding, the cytoskeleton, which gives a cell its shape and allows it to interact with its environment.

Concentrating on the cytoskeleton allowed the team to maximize the number and function of insulin-producing cells. In fact, some of the mice were cured for a year, according to Millman.

But the scientist admits that the results of their work will require further study and development before it can be used on humans. Millman and his team have no timeline for when their new method could be ready.

That means diabetics will have to wait a while longer.

Eventually, however, the team hopes to find an automated way to produce enough cells to allow diabetics to control the disease on their own.

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